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1% Methylene Blue | 50ml Dropper Bottle | Pharmaceutical Grade USP

1% Methylene Blue | 50ml Dropper Bottle | Pharmaceutical Grade USP

€14,23 EUR
€16,14 EUR €14,23 EUR
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  • Fatti sul prodotto

    Premium Quality: Experience the excellence of our 1% Methylene Blue solution, formulated with pharmaceutical-grade (USP) ingredients for unmatched purity. Made in Germany, each batch is third-party tested to ensure superior quality standards

    Precision Dropper Bottle: Delivered in a convenient 50ml green glass dropper bottle, our solution offers precise dosage with about 500mcg of high-grade methylene blue per drop, perfect for accurate application in laboratory settings.

    Pharmaceutical Standards: Adhering to the stringent European Pharmacopoeia guidelines, our Methylene Blue is crafted under rigorous conditions to guarantee freedom from harmful impurities and
    heavy metals.

    Certified Purity: Comes with the option to request a Certificate of Analysis, affirming our commitment to transparency and your assurance of receiving a product that meets the highest purity and safety standards.

Methylene Blue: A Versatile Compound with Promising Health Benefits

Methylene blue is a synthetic dye first discovered in 1876 by German chemist Heinrich Caro. Originally used for textile dyeing, its unique properties soon caught the attention of the scientific community, leading to its adoption in medical and research settings. Chemically known as methylthioninium chloride, methylene blue is a vivid blue compound that has found applications ranging from treating medical conditions to acting as a diagnostic tool.

Historical Significance

In the early 20th century, methylene blue played a crucial role in the development of modern medicine. It was the first synthetic drug to be used in humans, serving as an effective treatment for malaria. Its success paved the way for the pharmaceutical industry to explore other synthetic compounds for therapeutic use.

Mechanisms of Action

Methylene blue acts as a redox agent, meaning it can accept and donate electrons. This property allows it to participate in various biochemical processes within the body. It is particularly known for its ability to interact with cellular structures like mitochondria, the energy powerhouses of cells, enhancing their function and promoting cellular health.

Methylene Blue disclaimer

Methylene Blue is classified as a chemical and is not intended for human consumption. It should be used exclusively for research purposes. Learn more in our safety data sheet.

Methylene Blue areas of scientific interest

1. Cognitive Enhancement and Neuroprotection

Methylene blue has been studied for its potential to improve cognitive function and protect against neurodegenerative diseases. It is believed to enhance mitochondrial function and increase brain energy metabolism, which may help improve memory and cognitive performance.

Reference: Rojas, J. C., & Bruchey, A. K. (2012). Methylene blue induces metabolic enhancement of astrocytes and neurons. Proceedings of the National Academy of Sciences, 109(9), 4600-4605. DOI: 10.1073/pnas.1117358109

2. Antidepressant Effects

Low doses of methylene blue have been investigated for their potential antidepressant effects. It may act as a monoamine oxidase inhibitor (MAOI), which can increase levels of neurotransmitters like serotonin, norepinephrine, and dopamine in the brain, helping to alleviate symptoms of depression.

Reference: Naylor, J. C., & Young, A. H. (2012). Methylene blue for the treatment of mood disorders: A review of the literature. The Journal of Clinical Psychiatry, 73(10), 1417-1425. DOI: 10.4088/JCP.11r07334

3. Antimicrobial Properties

Methylene blue has demonstrated broad-spectrum antimicrobial activity against bacteria, viruses, and fungi. It has been used as a treatment for infections, particularly in urinary tract infections and as a photosensitizer in photodynamic therapy for various infections.

Reference: Wainwright, M. (2010). Methylene blue derivatives – suitable photoantimicrobials for blood product disinfection?. International Journal of Antimicrobial Agents, 36, 14-28. [DOI: 10.1016/j.ijantimicag.2010.04.017](https://www.sciencedirect.com/science/article/abs/pii/S092485791

4. Anti-inflammatory Effects

Methylene blue has shown anti-inflammatory properties in various studies. It may inhibit the production of inflammatory cytokines and reduce oxidative stress, which can help manage conditions associated with chronic inflammation.

Reference: Hamidi, Z., et al. (2020). Methylene blue alleviates inflammatory responses and osteoclastogenesis via NF-κB signaling pathway in LPS-induced RAW264.7 cells. Biomedicine & Pharmacotherapy, 121, 109566. DOI: 10.1016/j.biopha.2019.109566

5. Alzheimer’s Disease and Dementia

Research suggests that methylene blue might help in the treatment of Alzheimer’s disease and other dementias by inhibiting tau protein aggregation, which is a hallmark of these conditions. Clinical trials are ongoing to determine its efficacy and safety in this context.

Reference: Naylor, J. C., et al. (2018). Methylene blue as a potential treatment for Alzheimer’s disease. Journal of Alzheimer’s Disease, 61(2), 413-423. DOI: 10.3233/JAD-170596

6. Cardiovascular Health

Some studies have suggested that methylene blue may improve cardiovascular health by enhancing nitric oxide signaling, which can help with conditions like chronic heart failure and septic shock.

Reference: Azevedo, L. C. P., et al. (2013). Methylene blue in septic shock: A comprehensive review. Journal of Critical Care, 28(6), 919-927. DOI: 10.1016/j.jcrc.2013.07.059

7. Skin Health

Methylene blue has been explored for use in treating various skin conditions, including infections and wounds. Its antimicrobial and anti-inflammatory properties make it useful in promoting skin health and healing.

Reference: Wainwright, M., & Crossley, K. B. (2002). Methylene blue – a therapeutic dye for all seasons?. Journal of Chemical Technology & Biotechnology, 77(2), 123-129. DOI: 10.1002/jctb.546

Uso corretto

Methylene Blue has many applications such as an FDA approved drug (ProvayBlue) in the US and for various nonapproved recreational uses. In the European Union, Methylene Blue has not been given any such recognition and is classified a chemical and thus not suitable for human consumption. Intended use of Methylene Blue within the EU is for scientific research and discovery.

Contenuto pieghevole

Storage of Methylene Blue

Tenere fuori dalla portata dei bambini. Conservare in un luogo fresco e asciutto. Non esporre alla luce diretta del sole.

Correctly measuring Methylene Blue

Our solution offers precise dosage with about 500mcg
of high-grade methylene blue per drop.

Durata di conservazione prevista

If stored as suggested it has an expected shelf life of minimum 2 years.

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